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New Research on Breast Cancer Risk

Researchers continue to look for the habits and environmental conditions that could increase chances of getting cancer.

Irregular Work Hours
A Danish study in 2001 reported that irregular working hours, including working at night, increased the risk of breast cancer by 1.5 percent.

Age at Pregnancy and Childbirth
Pregnancy and childbirth are also being studied in relation to onset of breast cancer. Researchers have previously thought that the period of highest risk is the time before the first pregnancy. Studies during the 1990s concluded that a woman's breast is very sensitive to carcinogenic influences before she delivers her first baby. Some of these studies said that a woman who has an induced abortion before delivering her firstborn child is at a higher risk of developing breast cancer because of the increase in hormone levels.

But a Danish study, published in Epidemiology on January 12, 2001, found a link between any age that a woman bears children and her risk of breast cancer. That study found that the risk of cancer was lowered ten years after the first childbirth. It concluded that the early reproductive years, rather than just the pre-birth years, constitute the critical period of high risk.

Ethnic Groups At Higher Risk?
Women from ethnic minority groups appear to suffer from more troublesome forms of breast cancers than Caucasian women.

A Seattle study of 90,000 women showed that cancer cells differ by ethnicity, but researchers from the Fred Hutchinson Cancer Research Center said these differences may be due to both genes and environment.

Compared to Caucasian women, African-American women are less likely to be diagnosed with breast cancer, but more likely to die from the disease once it is found.

Ductal carcinoma represents about 80 percent of all breast cancers and is usually more aggressive than lobular carcinoma, which accounts for another ten to fifteen percent of breast cancers.

Researchers in this study found that Caucasian women tended to have a more favorable prognosis than women of all other ethnic groups except Native Americans.
The reason remains illusive. The discrepancies are currently believed to be a combination of biological, genetic, environmental, and lifestyle differences.

Resources

American Cancer Society. (2002). Some ethnic groups may have more aggressive breast cancers . Retrieved August 12, 2002, from
www.cancer.org/eprise/main/docroot/NWS/content/NWS_1_1x_
Some_Ethnic_Groups_May_Have_More_Aggressive_Breast_Cancers.

Russo, J., Russo, I.H. (1994). Toward a physiological approach to breast cancer prevention. Cancer Epidemiology, Biomarkers and Prevention, 3, 353-364. Retrieved August 12, 2002, from www.pregnantpause.org/safe/abckahl.htm.

Wohlfahrt, J., Melbye, M. (2001). Age at any birth is associated with breast cancer risk. Retrieved August 12, 2002, from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
PubMed&list_uids=11138822&dopt=Abstract.

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