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Lupus Treatments: Chinese Medicines Augment Western Medicines Systemic lupus erythematosis attacks the autoimmune systems of an estimated one million Americans. In China, this number is approximately five times as large. Contemporary medical protocols for treatment of this disorder usually involve the use of immunosuppressive agents either alone or in conjunction with corticosteroids, such as prednisone. Other chemical treatments include cyclophosphamide, methotrexate, hormonal and anti-hormonal therapies, and even the use of drugs more commonly associated with the treatment of malaria. Even as medical technology advances result in new diagnostic tools and new drug formulations, affected populations have an increased interest in more traditional Chinese remedies for this condition and its manifestations. Chinese medical texts dating from the middle of the 17th century (Qing Dynasty, 1662-1722) identified the illness and correlated its occurrence with warm weather. Chinese practitioners felt that heat was the primary trigger. In point of fact, many of the herbal formulas utilized in Chinese medicine for treat of the condition were developed during the Ming Dynasty (1368-1644) in response to epidemics of various fever-related sicknesses, with SLE being viewed as a "warm" disease. During the late 1990s, Chinese researchers conducted three clinical trials using classic herbal formulas to measure the effectiveness of these remedies in conjunction with Western medicine (i.e., prednisone). The herbal preparations all contained the herbs moutan and rehmannia—both of which had been identified as the traditional methods of treating skin redness as the result of heat in the blood. Other combinations were added in each of the three trials to assess whether various measurable components of lupus were affected in any way. At the conclusion of the studies, researchers noted that the test groups using herbal formulas in conjunction with prednisone showed measurable improvements in symptoms and were able to decrease or end the need for medication. A number of clinically measurable results were obtained. In one study, the neopterin levels of SLE patients—usually higher than healthy individuals—was reduced when the herbal therapy was utilized. A second significant result showed that interleukin-2R (another stimulant of the immune system) also had lower measurements. Many of the symptoms associated with lupus (skin rashes, renal obstruction, and arthritis, for example) also improved using the combination of herbal preparations and Western medicine. Significantly, all three groups reported fewer and less severe side effects from using the herbal-medicinal combination, than those who were treated with conventional drug therapy. These studies provide new avenues for future research in the application of alternative medical approaches to a contemporary medical issue. By combining the wisdom of Chinese herbalists with Western pharmaceutical advances, researchers may well find more effective and longer-lasting therapies to fight this life-altering illness. Resource Dharmananda, S. (2001). Treatment of systemic lupus erthematosis (SLE) with Chinese herbs. Internet Journal of the Institute for Traditional Medicine, August 2001. Retrieved August 23, 2002, from www.itmonline.org/arts/lupus.htm.

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