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Innovative Glass Therapy to Repair Bone and Treat Arthritis The latest research into new ways of repairing arthritis-linked bone damage has produced some remarkable results using the simplest of substances: glass. Scientists at the University of Missouri-Rolla are currently developing special microscopic glass spheres that are suitable for injecting into arthritic joints, crushed vertebrae and other areas of damaged bone. The University's Professor Emeritus of Ceramic Engineering, Dr. Delbert Day, compares the process with "a caulking gun (used) to repair the cracks in your bathroom." He continues, "Now think of injecting a non-harmful but similar substance into crushed vertebrae to fill in the space and cracks." The concept is relatively simple. The procedure involves combining microscopic glass particles with a polymer to produce a mixture that can be used to repair areas of damaged, diseased or broken bone. The glass-polymer would, in effect, fill the cracks and "glue back together" the broken fragments of bone. The glass mixture hardens into a robust substance resembling human bone, which bonds to the existing bone. Researchers at UMR, encouraged by the potential of glass therapy for treating advanced stages of arthritis, have also embarked upon a program to develop biodegradable glass spheres, approximately one-fifth to one-tenth the diameter of a human hair. These microscopic, radioactive spheres are designed to be injected into diseased bone and to deliver radiation to the targeted arthritic joint. One of the major benefits of this type of procedure, according to Dr. Day, is that the "glass beads confine all of the radioactivity to the diseased joint." Also, because of their biodegradable nature, the spheres, having delivered radiation to the bone, simply react with the body fluids and are then safely eliminated from the body. Will biodegradable glass beads become commonplace in the treatment of arthritis? According to Dr. Day, glass therapy offers great potential for people who suffer from arthritis. He concludes, "What we investigate and see in the laboratory, compared to what has been seen in experiments on animals, is encouraging." Do You Suffer from Arthritis of the Knee? A recent study has revealed a link between inactivity and increased disability in those who suffer from osteoarthritis of the knee. The importance of muscle strength in preventing physical decline in those suffering from osteoarthritis of the knee is highly significant. Research carried out at the Netherlands Institute of Health Services Research Center, Utrecht, confirmed that withdrawal from physical activity to avoid discomfort and pain can result in marked physical deterioration and muscle degeneration in the osteoarthritis patient. The study concluded that overall avoidance of physical activity accounted for a 21.5 percent variance in disability. These statistics also pointed to the fact that withdrawal from physical activity tends to give rise to a vicious circle of increased avoidance and further weakening of the muscles. Resource Pro Health, Inc. (2002). Study confirms link between lack of exercise and increased disability. Retrieved July 10, 2002, from www.arthritissupport.com/library/showarticle.cfm/id/413. Pro Health, Inc. (2002). New glass therapy can repair bone, treat arthritis. Retrieved July 10, 2002, from www.arthritissupport.com/library/showarticle.cfm/id/410.

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